St. Luke’s Deemed Safest Hospital System in Pennsylvania

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Photo caption: Representatives from the six St. Luke’s campuses accept the 2025 Excellence in Patient Safety Recognition awards.

Six St. Luke’s University Health Network hospitals – the most of any health network in the state – were honored by the Hospital and Healthcare Association of Pennsylvania (HAP) for exemplary results in delivering safe patient care.

Now in its seventh year, HAP’s Excellence in Patient Safety Recognition program honored 22 of the commonwealth’s top-performing hospitals that have demonstrated low rates of healthcare-associated infections.

The six St. Luke’s hospitals recognized for exemplary safe patient care include:

This is the fifth consecutive year that St. Luke’s Anderson Campus has been honored through the Excellence in Patient Safety Recognition program. The hospital’s team received special recognition for demonstrating consistent, outstanding patient safety outcomes annually from 2021–2025.

St. Luke’s University Hospital’s Bethlehem Campus has been honored all seven years. The Bethlehem Campus is the only hospital in the state to earn this important designation every year that HAP has awarded it.

“There can be only one #1, and by these objective measures, it is St. Luke’s,” said St. Luke’s Senior Vice President and Chief Quality Officer Donna Sabol. “This state recognition comes on the heels of being recognized by the federal Agency for Healthcare Research and Quality as one of the nation’s top three high performing health systems for safety and quality.”

The 2025 honorees were selected based on their performance during 2024.

“Hospitals’ top priority is ensuring high-quality, safe care for their communities,” HAP President and CEO Nicole Stallings said. “HAP proudly recognizes the Pennsylvania hospital teams that went above and beyond to demonstrate their commitment to continuous quality and safety improvement and achieved exceptional results.”

HAP announced the 2025 Excellence in Patient Safety Recognition recipients Oct. 8 during its Patient Safety, Quality, and Equity Symposium in Harrisburg.

HAP identifies top-performing hospitals using data from the Centers for Disease Control and Prevention’s National Healthcare Safety Network. To be recognized, hospitals must perform better than the mean standardized infection ratio in three key measures: central line-associated bloodstream infections, catheter-associated urinary tract infections, and occurrences of Clostridioides difficile.

About St. Luke’s

Founded in 1872, St. Luke’s University Health Network (SLUHN) is a fully integrated, regional, non-profit network with annual net revenue of more than $4 billion. With 23,000+ employees at 16 hospital campuses and 350+ outpatient sites, it is the Lehigh Valley’s biggest employer.

The Network’s service area includes 11 counties in two states: Lehigh, Northampton, Berks, Bucks, Carbon, Montgomery, Monroe, Schuylkill and Luzerne counties in Pennsylvania and Warren and Hunterdon counties in New Jersey. St. Luke’s hospitals operate the largest network of trauma centers in Pennsylvania, with the Bethlehem Campus being home to St. Luke’s Children’s Hospital.

Dedicated to advancing medical education, St. Luke’s is the preeminent teaching hospital in central-eastern Pennsylvania. In partnership with Temple University, the Network established the Lehigh Valley’s first and only four-year medical school. It also operates the nation’s oldest School of Nursing, established in 1884, and 50+ fully accredited graduate medical educational programs with 500+ residents and fellows.

St. Luke’s has been named a Leapfrog Group and Healthgrades Top Hospital and a Newsweek World’s Best Hospital. It is the only Lehigh Valley-based health care system to earn Medicare’s five-star ratings (the highest) for quality, efficiency and patient satisfaction. In 2025, the Network earned straight A’s from Leapfrog across all of its 11 acute care hospitals. It has earned 100 Top Hospital designations from Premier 11 years in a row, including in 2021 when its flagship University Hospital was identified as THE #1 TEACHING HOSPITAL IN THE COUNTRY. Utilizing the Epic electronic medical record (EMR) system for both inpatient and outpatient services, the Network is a multi-year recipient of the Most Wired award recognizing the breadth of SLUHN’s information technology applications such as telehealth, online scheduling and online pricing information.

Information provided to TVL by:
Gary Blockus